Cell nucleus was infiltrated with a fluid which damages the nonhistones-proteins in it. What structure of the nocleolus will be damaged first of all?

Cell nucleus was infiltrated with a fluid which damages the nonhistones-proteins in it. What structure of the nocleolus will be damaged first of all?

1.  Nuclear pores


2.  Chromatin


3.  DNA


4.  RNA


5.  *Nuclear matrix